کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5789241 1414305 2015 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Nanopore DNA sequencing: Are we there yet?
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی (عمومی)
پیش نمایش صفحه اول مقاله
Nanopore DNA sequencing: Are we there yet?
چکیده انگلیسی
Nanopores have been studied as a unique DNA sequencing technology that can quickly read long stretched DNA sequences. A DNA molecule could pass through a nanopore in a speed of microsecond per base and even faster. With this speed, a human genome can potentially be sequenced by one nanopore in <1 h. In contrast to next-generation DNA sequencing (NGS), the nanopore sequencing is enzyme free without need of sample amplification due to its single-molecule nature. The nanopore sequencing has been envisioned as a new generation of DNA sequencing technology in the post-NGS era. This progress focuses on status quo of the nanopore DNA sequencing and discusses the opportunities and challenges in this rapidly growing field.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Science Bulletin - Volume 60, Issue 3, February 2015, Pages 296-303
نویسندگان
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