کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5791154 1554084 2015 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effects of intergenic single nucleotide polymorphisms in the fast myosin heavy chain cluster on muscle fiber characteristics and meat quality in Berkshire pigs
ترجمه فارسی عنوان
اثرات پلی مورفیسم تک ژن های تک سلولی در خوشه زنجیره سنگین میوزین سریع بر روی ویژگی های فیبر عضله و کیفیت گوشت در خوک های برکشایر
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش تغذیه
چکیده انگلیسی
The heterogeneity of myosin heavy chain (MyHC) isoforms is closely related to muscle fiber characteristics, and meat quality in pigs. The fast MyHC gene cluster on porcine chromosome 12 contains MYH2, MYH1, and MYH4, which encode three fast MyHC isoforms expressed in adult skeletal muscle. Here, we identified four intergenic single nucleotide polymorphisms (SNPs) in the gene cluster. Of these, SNP1 and SNP2, which were located near MYH2, were genotyped in 199 Berkshire pigs. SNP1 were significantly associated with the total fiber number (P = 0.046) and intramuscular fat contents (P = 0.041), and SNP2 had significant effects on type I fiber number/area compositions (P = 0.039 and P = 0.041, respectively), water holding capacity (drip loss, P = 0.045; cooking loss, P = 0.001), and meat color (P = 0.003). Taken together, our results suggest that the intergenic SNPs near MYH2 can affect muscle fiber formation and meat quality by modifying the regulatory elements of this gene cluster in pigs.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Meat Science - Volume 110, December 2015, Pages 224-229
نویسندگان
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