کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5794831 1110500 2014 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Clastogenic effects of Trypanosoma brucei brucei and Trypanosoma evansi mixed infection in bone marrow of Wistar rats
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
پیش نمایش صفحه اول مقاله
Clastogenic effects of Trypanosoma brucei brucei and Trypanosoma evansi mixed infection in bone marrow of Wistar rats
چکیده انگلیسی


- Rats were infected with T. evansi and T. brucei brucei.
- Clastogenic effects were evaluated in BM cells using the micronucleus assay.
- Formation of MN-PCEs in the BM cells significantly (P < 0.05)
- Mixed infection induced formation of MN-PCEs increase by about 1.33 fold when compared with single infections.

The clastogenic effect of mixed infection of Trypanosoma evansi and Trypanosoma brucei brucei in the bone marrow (BM) cells of Wistar albino rats was investigated. Clastogenic effects were observed in the BM cells using the micronucleus assay. The findings indicate that T. evansi, T. b. brucei and mixed infection with both parasites induced the formation of micronucleated polychromatic erythrocyte (MN-PCEs) in the BM cells significantly (P < 0.05) by 60, 63 and 81 micronuclei/1000 PCE respectively. Mixed infection induced formation of MN-PCEs increase by about 1.33 fold when compared with single infections of T. b. brucei and T. evansi. These data give a preliminary evidence of possible genotoxic effects in trypanosomiasis.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Research in Veterinary Science - Volume 97, Issue 3, December 2014, Pages 550-553
نویسندگان
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