کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5795102 | 1110505 | 2012 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Age, scrapie status, PrP genotype and follicular dendritic cells in ovine ileal Peyer's patches
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم دامی و جانورشناسی
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![عکس صفحه اول مقاله: Age, scrapie status, PrP genotype and follicular dendritic cells in ovine ileal Peyer's patches Age, scrapie status, PrP genotype and follicular dendritic cells in ovine ileal Peyer's patches](/preview/png/5795102.png)
چکیده انگلیسی
Follicular dendritic cells (FDCs) residing within ileal Peyer's patches (PPs) are of crucial relevance for sheep scrapie early pathogenesis and subsequent scrapie prion neuroinvasion. In this study, ileal PP follicles were significantly more numerous in lambs than in adult Sarda breed sheep, with significant differences being also found in lymphoid follicle area, perimeter and FDC density. Furthermore, PrPd deposition within ileal PPs and host's PrP genotype did not significantly influence these parameters. We conclude that age significantly affects FDC density in ileal PPs from Sarda breed ovines, independently from host's scrapie status and PrP genotype.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Research in Veterinary Science - Volume 93, Issue 2, October 2012, Pages 853-856
Journal: Research in Veterinary Science - Volume 93, Issue 2, October 2012, Pages 853-856
نویسندگان
Giuseppe Marruchella, Ciriaco Ligios, Giovanni Di Guardo,