Clinical efficacy of florfenicol on caprine pasteurellosis

The aim of this clinical study was to investigate the efficacy of florfenicol (FFC) in the treatment of caprine pasteurellosis (CP) in goats of different age and sex. Forty Saanen goats of both sexes, aged 2 months to 2 years, with natural infection by Pasteurella multocida in the Afyonkarahisar province of Turkey were used in this study. Prior to the study, animals were randomly divided into two groups: 30 animals assigned to the FFC group were injected intramuscularly with FFC, two doses of 20 mg/kg body weight at a 48-h interval. The remaining 10 animals, not medicated with any antibiotic, served as a control group (C). All animals assessed at baseline and on days 1 (first day of study), 3 (third day of study), 7 and 10. FFC-treated goats showed a significant clinical improvement when compared to controls (P < 0.05). All the animals in C which still showed signs of CP were crossed over to FFC treatment at the end of the study.