Sex-specific differences in the dynamics of cocaine- and amphetamine-regulated transcript and nesfatin-1 expressions in the midbrain of depressed suicide victims vs. controls

► CART and nesfatin/NUCB2 colocalized in the human EWcp. ► EWcp-CART mRNA is higher in drug-free suicide victims vs. controls in both sexes. ► EWcp-NUCB2 mRNA content is higher in male suicides vs. controls. ► EWcp-NUCB2 mRNA content is lower in female suicide victims vs. controls.