To poly(I:C) or not to poly(I:C): Advancing preclinical schizophrenia research through the use of prenatal immune activation models

► The prenatal poly(I:C) model is one of the currently available immune activation models in rodents. ► The model mimics multiple brain and behavioral abnormalities implicated in schizophrenia. ► The model may help to improve symptomatic and preventive interventions for schizophrenic disease.