JM-20, a novel benzodiazepine-dihydropyridine hybrid molecule, protects mitochondria and prevents ischemic insult-mediated neural cell death in vitro

The neuroprotective effects of JM-20 involve both anti-excitotoxic and anti-Ca2+ effects at neuronal level, as well as mitoprotective effects against Ca2+-induced impairment in association with ATP preservation.52