کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5831149 | 1559657 | 2013 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Monoterpene pyridine alkaloids and phenolics from Scrophularia ningpoensis and their cardioprotective effect
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موضوعات مرتبط
علوم پزشکی و سلامت
داروسازی، سم شناسی و علوم دارویی
داروشناسی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Monoterpene pyridine alkaloids and phenolics from Scrophularia ningpoensis and their cardioprotective effect Monoterpene pyridine alkaloids and phenolics from Scrophularia ningpoensis and their cardioprotective effect](/preview/png/5831149.png)
چکیده انگلیسی
Scrophularianines A-C (1-3), three new unusual monoterpene pyridine alkaloids with cyclopenta [c] pyridine skeleton reported from the genus Scrophularia for the first time, together with 15 known compounds (4-18), were isolated from the extract of Scrophularia ningpoensis. Their structures were elucidated on the basis of extensive analyses of spectroscopic evidences. The biogenetic relationship between monoterpene pyridine alkaloids and iridoids was proposed preliminarily. The myocardial protective bioassay indicated that compounds 13 and 14 with a concentration of 10â 4 M exhibited significantly protective effect against H2O2-induced apoptosis in cardiomyocytes.
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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fitoterapia - Volume 88, July 2013, Pages 44-49
Journal: Fitoterapia - Volume 88, July 2013, Pages 44-49
نویسندگان
Ling-Juan Zhu, Yun-Long Hou, Xiu-Yu Shen, Xiao-Dong Pan, Xue Zhang, Xin-Sheng Yao,