Cytotoxic sesquiterpenes from Hedychium spicatum: Isolation, structure elucidation and structure-activity relationship studies

Six new sesquiterpenes (1-6) along with fifteen known compounds (7-21) were isolated from the hexane extract of Hedychium spicatum. All the isolates were tested for their cytotoxic activities against panel of human cancer cell lines(A-549, B-16, Hela, HT-29, NCI-H460, PC-3, IEC-6 and L-6).249