کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5831513 | 1122153 | 2012 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
New isocoumarins and alkaloid from Chinese insect medicine, Eupolyphaga sinensis Walker
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موضوعات مرتبط
علوم پزشکی و سلامت
داروسازی، سم شناسی و علوم دارویی
داروشناسی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Two new isocoumarins (1 and 2), a new alkaloid (3), and a known N-acetyldopamine dimer (4) were isolated from the ethyl acetate extract of Chinese insect medicine Eupolyphaga sinensis. Their structures were elucidated on the basis of detailed spectroscopic investigations, such as 1D- and 2D NMR spectroscopy, as well as by means of HR-MS. The structure of 1 was firmly confirmed by X-ray crystallography, and the absolute configuration was revealed by experimental and computational optical rotation analyses. Cytotoxicities of 1-4 were measured in vitro against 10 selected cancer cell lines.
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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fitoterapia - Volume 83, Issue 7, October 2012, Pages 1275-1280
Journal: Fitoterapia - Volume 83, Issue 7, October 2012, Pages 1275-1280
نویسندگان
Hai-Long Jiang, Xiao-Hong Luo, Xiao-Zheng Wang, Jun-Li Yang, Xiao-Jun Yao, Phillip Crews, Frederick A. Valeriote, Quan-Xiang Wu,