Effects of 4,4′-dichloro-diphenyl diselenide (ClPhSe)2 on toxicity induced by mercuric chloride in mice: A comparative study with diphenyl diselenide (PhSe)2

► The effects of (ClPhSe)2 on the toxicity induced by HgCl2 were investigated. ► The results of (ClPhSe)2 were compared with (PhSe)2. ► (ClPhSe)2 presented better toxicological results in comparison to (PhSe)2. ► The introduction of chloro in the aromatic ring of (PhSe)2 reduced its toxicity.