کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5849093 | 1130706 | 2014 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Potential matrix metalloproteinase inhibitors from edible marine algae: A review
ترجمه فارسی عنوان
مهار کننده های ماتریکس متیل پروتئیناز پتانسیل از جلبک دریایی خوراکی: یک بررسی
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کلمات کلیدی
جلبک دریایی، متالوپروتئیناز ماتریکس، فلوترانین، پلی ساکارید سولفات، متاستاز، سرطان، التهاب
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
بهداشت، سم شناسی و جهش زایی
چکیده انگلیسی
Matrix metalloproteinases are endopeptidases which belong to the group of metalloproteinases that contribute for the extra-cellular matrix degradation, and several tissue remodeling processes. An imbalance in the regulation of these endopeptidases eventually leads to several severe pathological complications like cancers, cardiac, cartilage, and neurological related diseases. Hence inhibitory substances of metalloproteinases (MMPIs) could prove beneficial in the management of above specified pathological conditions. The available synthetic MMPIs that have been reported until now have few shortcomings and thus many of them could not make to the final clinical trials. Hence a growing interest among researchers on screening of MMPIs from different natural resources is evident and especially natural products from marine origin. As there has been an unparalleled contribution of several biologically active compounds from marine resources that have shown profound applications in nutraceuticals, cosmeceuticals, and pharmaceuticals, we have attempted to discuss the various MMPIs from edible sea-weeds.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Environmental Toxicology and Pharmacology - Volume 37, Issue 3, May 2014, Pages 1090-1100
Journal: Environmental Toxicology and Pharmacology - Volume 37, Issue 3, May 2014, Pages 1090-1100
نویسندگان
Noel Vinay Thomas, Panchanathan Manivasagan, Se-Kwon Kim,