Antitumor activity of glycyrol via induction of cell cycle arrest, apoptosis and defective autophagy

- Glycyrol induces cell cycle arrest and apoptosis.
- Glycyrol activates JNK/p38 to promote caspase-mediated apoptosis.
- AMPK activation retards glycyrol-induced apoptosis.
- Glycyrol induces defective autophagy.
- Glycyrol suppresses tumor growth in a nude mouse tumor xenograft model.