کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5850851 | 1561781 | 2014 | 4 صفحه PDF | دانلود رایگان |
- Subject with known allergies to sulfonamides, sulfites and various foods.
- Hypersensitivity to taurine above a threshold level demonstrated in challenge tests.
- Hypersensitivity to acesulfame potassium in an apparently dose dependent manner.
- Suggested mechanisms for the taurine allergy were provided.
A case study is reported whereby an individual with known sulfite and sulfonamide allergies develops hypersensitivity to taurine above a threshold level as well as to the non-nutritive sweetener acesulfame potassium, compounds that are not normally associated with allergic reactions. Sulfites, sulfonamides, taurine and acesulfame potassium all contain a SO3 moiety. Challenge tests provide evidence for the hypersensitivities to taurine and acesulfame potassium. The subject is also allergic to thiuram mix and thimerosal, sulfur containing compounds, as well as to various food products. This may be the first case where hypersensitivities to taurine and acesulfame potassium have been documented and reported. Several mechanistic explanations are provided for the untoward reactions to taurine and acesulfame potassium.
Journal: Food and Chemical Toxicology - Volume 63, January 2014, Pages 240-243