Mutagenic/recombinogenic effects of four lipid peroxidation products in Drosophila

► The genotoxicity of four lipid peroxidation products was investigated. ► Acrolein, crotonaldehyde, 4-HHE and 4-ONE are genotoxic in Drosophila. ► Lipid peroxidation products revealed genotoxic effects. ► The Drosophila SMART assay was used as a tool.