Toxicological and mutagenic analysis of Artemisia dracunculus (tarragon) extract

► Results of the present study show that Tarragon contains mutagenic components. ► Occasional use is probably not dangerous, but in high doses it is not recommended. ► A dose-responsive increase in mutagenicity index was observed. ► Cancer risk is likely due to methylchavicol or possibly other genotoxic compounds. ► We confirmed the aforementioned using enzyme activity and liver morphology assay.