A high oxfendazole dose to control porcine cysticercosis: Pharmacokinetics and tissue residue profiles

► The pig plasma and tissue residue pattern after OFZ oral treatment at high dose used for cysticercosis was studied. ► The comparison of two different OFZ formulations was reported. ► OFZ and its metabolites FBZSO2 and FBZ were measured in the bloodstream after both treatments. ► Residual concentrations of OFZ and/or its metabolites FBZSO2 and FBZ were measured in all tissues. ► The OFZ use at this dose in pigs would require of an extended withdrawal time before deliver for human consumption.