Embryonic developmental toxicity of selenite in zebrafish (Danio rerio) and prevention with folic acid

► There is very few reports describing toxic effect of Se on fish in general and on zebrafish in particular. ► Selenite caused cardiac and neural defects in zebrafish embryos disturbing genomic DNA methylation. ► Supplementation of folic acid rescued selenite-induced developmental abnormality. ► It will provide the risk assessment and prevention of selenite-induced embryotoxicity.