Modulation of the effects of methylmercury on rat neurodevelopment by co-exposure with Labrador Tea (Rhododendron tomentosum ssp. subarcticum)

► Rats were exposed perinatally to methylmercury administered either alone or with a Rhododendron tomentosum extract. ► Co-exposure effects on pups growth and development, oxidative stress, glutamatergic system and neurobehaviour were assessed. ► Effects of co-exposure on molecular endpoint were very dependant on the developmental stage and endpoint assessed. ► However, modulation of molecular endpoints did not lead to significant alterations of MeHg's effects on rat neurobehaviour.