Evaluation of chemopreventive and cytotoxic effect of lemon seed extracts on human breast cancer (MCF-7) cells

► Aqueous methanol extract from lemon showed the highest radical scavenging activity. ► Lemon extracts are an excellent source to induce apoptosis in MCF-7 cancer cells. ► Lemon fractions are non-toxic to human normal breast cells. ► Lemons are a potential source to prevent human MCF-7 breast cancer cells.