Resveratrol preserves cardiac function, but does not prevent endothelial dysfunction or pulmonary inflammation after environmental tobacco smoke exposure

► Environmental tobacco smoke (ETS) impaired endothelial function and increased oxidative stress. ► ETS also caused lung and systemic inflammation that was not reversed by resveratrol. ► Resveratrol did help preserve cardiac function in pigs exposed to ETS. ► The French paradox may be due to resveratrol protection from cardiovascular effects of smoking.