Differential cholinesterase inhibition in the rat brain regions by dichlorvos and protective effect of Decalepis hamiltonii roots

► Dichlorvos shows differential inhibition of cholinesterase in rat brain regions. ► Decalepis hamiltonii root extract prevents DDVP-induced ChE inhibition. ► Antioxidants contribute to the protective effect of D. hamiltonii. ► Antioxidants can be used as nutraceuticals.