Inhalation of chlorine causes long-standing lung inflammation and airway hyperresponsiveness in a murine model of chemical-induced lung injury

► There are both early and late toxic effects of Cl2 depending on the dosage. ► Inhalation of Cl2 may lead to a long-standing airway hyperresponsiveness. ► The symptoms in Cl2-exposed mice are similar to those described for RADS in humans.