کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5868483 1563817 2015 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effect of adding the herb Achillea millefolium on mouthwash on chemotherapy induced oral mucositis in cancer patients: A double-blind randomized controlled trial
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
پیش نمایش صفحه اول مقاله
Effect of adding the herb Achillea millefolium on mouthwash on chemotherapy induced oral mucositis in cancer patients: A double-blind randomized controlled trial
چکیده انگلیسی

BackgroundOral mucositis (OM) is a debilitating side-effect of chemotherapy. It has different complications, including impairment of drinking, eating and even talking, sometimes so severe that physician stops the therapy.ObjectiveInvestigating the effect of Achillea millefolium distillate solution in the treatment of chemotherapy-induced OM.Interventions/methodsIn this randomized controlled trial, 56 cancer patients with chemotherapy-induced OM were randomly assigned into control and experimental groups in similar blocks based on the severity of OM. The experimental group gargled 15 mL of a mixture of routine solution and distilled A. millefolium 4 times a day for 14 days while the control group gargled 15 mL of routine solution. The severity of OM was assessed at three times before, 7 and 14 days after intervention. Data was analyzed using Wilcoxon, Kruskal-Wallis, Mann-Whitney U, Friedman, Chi-square and Fisher's exact tests.ResultsThe mean severity score of OM was 2.39 ± 0.875 in both groups at start of the study that was changed to 1.07 ± 0.85 and 0.32 ± 0.54 in the intervention group in days 7 and 14 (p < 0.001). However, the severity of OM was increased to 2.75 ± 0.87 and 2.89 ± 0.956 in the control group respectively (p < 0.001).ConclusionsA. millefolium distillate healed OM much more than the routine solution. Therefore, it is suggested to be used in patients with chemotherapy-induced OM.The study was registered in the Iranian Registry of Clinical Trials, Number: IRCT2013092214729N1.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Oncology Nursing - Volume 19, Issue 3, June 2015, Pages 207-213
نویسندگان
, , , ,