Simplifying the Complexity of Primary Hyperparathyroidism

Primary hyperparathyroidism (PHPT) is a common but complex endocrine disorder. Historically, many PHPT patients have been diagnosed only after a protracted period of manifesting significant signs and symptoms. However, today, PHPT is often found during routine serologic screening or evaluation for decreased bone mass. Knowledge of PHPT is essential to ensure appropriate patient evaluation and treatment and to prevent adverse outcomes of chronic, untreated disease. Elevated serum calcium with subsequent elevated parathyroid hormone levels usually brings the diagnosis to light. The diagnosis of PHPT can be challenging and medical management is available, but surgery is the only cure.