کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5876340 1566123 2015 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Immunoactivation at the Crossroads of Human Disease
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
پیش نمایش صفحه اول مقاله
Immunoactivation at the Crossroads of Human Disease
چکیده انگلیسی
It is becoming increasingly clear that immunoactivation, which evolved as a system of host defense against pathogens, can become dysregulated and promote the pathogenesis of diverse diseases with both known and unknown etiologies (eg, acquired immune deficiency syndrome, age-related macular degeneration, cancer, as well as aging). Immunoactivation seems to be a “common denominator” or general mechanism of pathogenesis and may explain the association and similarities in pathology among otherwise unrelated human diseases. Identification of general mechanisms of immunoactivation may lead to the development of new therapeutic strategies applicable to many diseases even before detailed knowledge of specific etiology and pathogenesis may be available.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The American Journal of Medicine - Volume 128, Issue 6, June 2015, Pages 562-566
نویسندگان
,