کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5883611 1150138 2016 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Original ArticleHigh Left Ventricular Filling Pressure on Doppler Echocardiography Is Associated With Graft Failure and Overall Mortality Following Kidney Transplantation
ترجمه فارسی عنوان
فشار داخل شکمی بطن چپ اصل در اکوکاردیوگرافی داپلر با شکستگی پیوند و مرگ و میر کلی به دنبال پیوند کلیه همراه است
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیهوشی و پزشکی درد
چکیده انگلیسی

ObjectiveAlthough E/e´ is prognostic of mortality in patients with end-stage renal disease (ESED), little is known about the prognostic implications of E/e´ following kidney transplant (KT). The objective of this study was to evaluate whether an elevated E/e´ is associated with graft function, postoperative hemodialysis, and overall mortality in end-stage renal disease patients following KT.DesignA retrospective observational study.SettingTertiary teaching hospital.ParticipantsIn total, 1,045 patients underwent KT at the authors' hospital between January 2006 and December 2013.InterventionNone.Measurements and Main ResultsPatients were divided into groups with an E/e´<15 or≥15, as assessed by preoperative echocardiography (median time from preoperative assessment of echocardiography to surgery: 37 days [IQR: 16-68 days]). Of 1,045 patients, 821 patients (78.6%) had an E/e´<15, and 224 patients (21.4%) had an E/e´≥15. Multivariate analysis indicated that age (odds ratio [OR]: 1.03; 95% confidence interval [CI]: 1.01-1.04, p = 0.001), diabetes mellitus (OR: 2.7; CI: 1.94-3.83, p<0.001), β-blocker (OR: 1.4; CI: 1.03-1.95, p = 0.034), left atrial dimension (OR: 1.07; CI: 1.04-1.11, p<0.001), and left ventricular mass index (OR: 1.02; CI: 1.01-1.03, p<0.001) are predictive of E/e´≥15. After adjustment using inverse probability of treatment weighting, E/e´≥15 also was associated independently with postoperative hemodialysis (OR: 2.0; 95% CI: 1.5-2.6, p<0.001), graft failure (OR: 1.7; 95% CI: 1.4-2.2; p<0.001), and overall mortality (hazard ratio [HR]: 3.2; 95% CI: 2.1-4.8, p<0.001).ConclusionsPreoperative E/e´ is a prognostic indicator of overall mortality in ESRD patients undergoing KT.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Cardiothoracic and Vascular Anesthesia - Volume 30, Issue 3, June 2016, Pages 585-591
نویسندگان
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