Xanthohumol suppresses inflammatory response to warm ischemia-reperfusion induced liver injury

► Xanthohumol reduces oxidative stress in hepatic ischemia/reperfusion (I/R) injury. ► Xanthohumol (XN) ameliorates I/R induced NFkappaB activation in the liver. ► XN inhibits expression of genes, which affect I/R-induced liver damage.