کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5895624 1154475 2013 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Current opinionDefective myometrial spiral artery remodelling as a cause of major obstetrical syndromes in endometriosis and adenomyosis
ترجمه فارسی عنوان
دیدگاه کنونی بازسازی مجدد شریان مجرای مارپیچی معیوب به عنوان علت سندرم های مهم سکته مغزی در آندومتریوز و آدنومایوز
کلمات کلیدی
آندومتریوز، آدنومایوز، قرار دادن عمیق، شریان های اسپیرال، سندرم های مامایی،
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شناسی تکاملی
چکیده انگلیسی

Endometriosis and adenomyosis are characterized by the presence of ectopic endometrium, but are also associated with functional and structural changes in the eutopic endometrium and inner myometrium. Alterations in the inner myometrium occurring in women with endometriosis and adenomyosis may be at the root of a defective remodelling of the myometrial spiral arteries from the onset of decidualization and result in vascular resistance and increased risk of defective deep placentation. The association of major obstetrical syndromes and different types of defective remodelling of the myometrial spiral arteries has been well documented. The possibility of a link between both endometriosis and adenomyosis and some major obstetric syndromes remains controversial because of at least two factors: first, changes of the inner myometrium are frequently present in women with endometriosis but the diagnosis requires high-resolution imaging such as magnetic resonance which is not routinely performed and second, patients with endometriosis are frequently subjected to prolonged hormone suppressive therapy. Indeed, there is evidence that pre-treatment with a Gonadotropin Releasing-Hormone analogue can improve the uterine microenvironment and implantation rate following IVF in infertile patients with endometriosis.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Placenta - Volume 34, Issue 2, February 2013, Pages 100-105
نویسندگان
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