Role of inflammatory gene polymorphisms in left ventricular dysfunction (LVD) susceptibility in coronary artery disease (CAD) patients

► NFKB1 -94 ATTG ins/del polymorphism is closely associated with LVD in CAD patients. ► IL6 -174 G/C and TNF-α -308 G/A polymorphisms are not associated with LVD. ► NFKB1 -94 ATTG1 allele may modulate disease severity by increasing LV remodeling.