Circulating cytokines in sarcoidosis: Phenotype-specific alterations for fibrotic and non-fibrotic pulmonary disease

► Circulating IL-5 is significantly decreased in patients with chronic sarcoidosis. ► Circulating IL-7 is significantly increased in chronic sarcoidosis patients. ► Circulating GM-CSF may be increased in patients with chronic sarcoidosis. ► Cytokine alterations differ between fibrotic and non-fibrotic pulmonary disease.