GD1a modulates GM-CSF-induced cell proliferation

► Exogenous addition of ganglioside GD1a increases granulocyte-macrophage colony-stimulating factor (GM-CSF)-induced cell proliferation. ► GM-CSF-induced proliferation is reduced by inhibiting ganglioside synthesis. ► Exogenous GD1a addition restores proliferative response of d-PDMP treated cells. ► GD1a modulates GMR-alpha expression. ► GD1a colocalize with GMR in FDC-P1 cells.