Interleukin-2 enhances angiogenesis and preserves cardiac function following myocardial infarction

► IV injection of rhIL-2 preserves LV fractional shortening and remodeling after MI. ► rhIL-2 enhances cardiac angiogenesis. ► rhIL-2 helps preserve the integrity and function of myocardium after MI. ► Proangiogenic effect of rhIL-2 correlated with the infiltration of NK cells.