Apheresis-inducible cytokine pattern change in severe, genetic dyslipidemias

► The effects of LDL-apheresis on plasma cytokines in severe dyslipidemia were evaluated ► HozFH, HtzFH, and HyperLp(a)lipoproteinemic patients with/without pre-existing CHD and AVD were treated with LDL-apheresis ► Plasma pro- and anti-inflammatory cytokines were measured before and after LDL-apheresis ► The observed cytokines changes are probably due to a direct/indirect effect of LDL-apheresis ► LDL-apheresis induced anti-inflammatory and anti-atherogenic changes in cytokines profile.