Inflammation-related proteins in the blood of extremely low gestational age newborns. The contribution of inflammation to the appearance of developmental regulation

► The concentrations of inflammation-related proteins in the blood of extremely low gestational age newborns tend to vary with gestational age and postnatal age during the first two postnatal weeks. ► The most common pattern of variation with gestational age in this narrow gestational range of 23-27 completed weeks is a decrease with increasing gestational age. ► The concentrations of these inflammation-related proteins tend to be higher in newborns whose placenta had histologic inflammation than in newborns whose placenta was not inflamed.