The mode of action of juvenile hormone and ecdysone: Towards an epi-endocrinological paradigm?

► Chromatin modification represents the essence of epigenetics. ► Chromatin-modifying enzymes are present in insects. ► How their activity is regulated is poorly understood. ► Hypothesis: Juvenile hormone and ecdysteroids have a role in epigenetics. ► Epigenetics complements classical arthropod endocrinology.