کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5901320 1568917 2013 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The pituitary-interrenal axis of fish: A review focusing on the lamprey and flounder
ترجمه فارسی عنوان
محور هیپوفیز - اینترنالال ماهی: بازبینی متمرکز بر لگن و ماهیگیری
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی علوم غدد
چکیده انگلیسی
In fish, the pituitary-interrenal axis is associated with stress response and a variety of biological processes such as metabolism, immune response, and growth. The major hormones involved in this axis are adrenocorticotropic hormone (ACTH), released from the pars distalis of the pituitary gland, and corticosteroid, released from the interrenal gland that is embedded in the head kidney in ray-finned fish. The ACTH signal, by which corticosteroid release is stimulated, is transmitted by melanocortin (MC) receptors on interrenal cells. Thus, the interaction of ACTH and MC receptors is the pivotal event for interrenal cells. Knowledge about ACTH and MC receptors in lamprey, cartilaginous fish, and ray-finned fish is available, and it suggests the pituitary-interrenal axis was established early in vertebrate evolution. Moreover, the data, including our recent results from flounders and lampreys, provide interesting features about ligand-receptor interactions. This review focuses on the characteristics of ACTH, the proopiomelanocortin gene encoding ACTH, and the MC receptor, and it is mostly based on the results of our investigations.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: General and Comparative Endocrinology - Volume 188, 1 July 2013, Pages 54-59
نویسندگان
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