کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5905155 | 1159854 | 2016 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Sex biased expression of ghrelin and GHSR associated with sexual size dimorphism in yellow catfish
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
WPTGHSRblastxmRNAcDNA - cDNAPelteobagrus fulvidraco - fulvidraco Pelteobagrusmessenger RNA - RNA messengerdeoxyribonucleic acid - اسید deoxyribonucleicRNA - اسید ریبونوکلئیکribonucleic acid - اسید ریبونوکلئیکmolecular evolutionary genetics analysis - تجزیه و تحلیل ژنتیک تکامل مولکولیanalysis of variance - تحلیل واریانسANOVA - تحلیل واریانس Analysis of variancebase pair - جفت پایهSexual dimorphism - دیمورفیسم جنسیFasting - روزه داریSEM - مدل معادلات ساختاری / میکروسکوپ الکترونی روبشیGhrelin - گرلینgrowth hormone secretagogue receptor - گیرنده ترشح هورمون رشد
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
ژنتیک
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Sex biased expression of ghrelin and GHSR associated with sexual size dimorphism in yellow catfish Sex biased expression of ghrelin and GHSR associated with sexual size dimorphism in yellow catfish](/preview/png/5905155.png)
چکیده انگلیسی
Sexual size dimorphism has been observed in many cultivable fish species including yellow catfish, in which male fish grow much faster than female fish. Ghrelin is a potent stimulator of pituitary growth hormone (GH) release and known to potentially promote food intake and body weight gain. In order to investigate the molecular mechanism of sexual size dimorphism in yellow catfish (Pelteobagrus fulvidraco), ghrelin and its functional receptor, growth hormone secretagogue receptor (GHSR) cDNAs were cloned. Real-time PCR indicated that both ghrelin and GHSR were more highly expressed in hypothalamus and gut of male fish than female. During normal larval development, expression of ghrelin and GHSR genes was significantly higher in males than in females. 17a-Methyltestosterone (MT) treatment enhanced the expression of ghrelin in female larval fish and GHSR in both sexes, whereas the expression of ghrelin in male larval fish increased in the beginning, then decreased as the treatment time prolonged. Furthermore, the expression of ghrelin and GHSR in male juvenile was significantly increased compared with female juvenile, in short and long term fasting periods, suggesting that male fish may have a better appetite than female during fasting. Our results demonstrate that sex difference in the expression of ghrelin and GHSR may be involved in sexual size dimorphism by regulating feeding and GH/IGF signaling in yellow catfish.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Gene - Volume 578, Issue 2, 10 March 2016, Pages 169-176
Journal: Gene - Volume 578, Issue 2, 10 March 2016, Pages 169-176
نویسندگان
Jin Zhang, Wenge Ma, Yan He, Junjie Wu, Farman Ullah Dawar, Fan Ren, Xiaohan Zhao, Jie Mei,