کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5906342 | 1159970 | 2013 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Indigenous and foreign Y-chromosomes characterize the Lingayat and Vokkaliga populations of Southwest India
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
Median-joiningNRYAMOVAMDSY-SNPHaplogroupSTRMitochondrial DNA - DNA میتوکندریاY-STR - STR-YSample size - اندازهی نمونهPhylogenetic analyses - تجزیه و تحلیل فیلوژنتیکCorrespondence analysis - تجزیه و تحلیل نامهanalysis of molecular variance - تجزیه و تحلیل واریانس مولکولیShort tandem repeat - تکرار کوتاه مدتMaximum likelihood - حداکثر احتمالmtDNA - دیانای میتوکندریاییMultidimensional scaling - مقیاس چند بعدیHaplotype - هاپلوتیپSingle nucleotide polymorphism - پلیمورفیسم تک نوکلئوتیدیSNP - چندریختی تک-نوکلئوتید
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
ژنتیک
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Indigenous and foreign Y-chromosomes characterize the Lingayat and Vokkaliga populations of Southwest India Indigenous and foreign Y-chromosomes characterize the Lingayat and Vokkaliga populations of Southwest India](/preview/png/5906342.png)
چکیده انگلیسی
Previous studies have shown that India's vast coastal rim played an important role in the dispersal of modern humans out of Africa but the Karnataka state, which is located on the southwest coast of India, remains poorly characterized genetically. In the present study, two Dravidian populations, namely Lingayat (NÂ =Â 101) and Vokkaliga (NÂ =Â 102), who represent the two major communities of the Karnataka state, were examined using high-resolution analyses of Y-chromosome single nucleotide polymorphisms (Y-SNPs) and seventeen short tandem repeat (Y-STR) loci. Our results revealed that the majority of the Lingayat and Vokkaliga paternal gene pools are composed of four Y-chromosomal haplogroups (H, L, F* and R2) that are frequent in the Indian subcontinent. The high level of L1-M76 chromosomes in the Vokkaligas suggests an agricultural expansion in the region, while the predominance of R1a1a1b2-Z93 and J2a-M410 lineages in the Lingayat indicates gene flow from neighboring south Indian populations and West Asia, respectively. Lingayat (0.9981) also exhibits a relatively high haplotype diversity compared to Vokkaliga (0.9901), supporting the historical record that the Lingayat originated from multiple source populations. In addition, we detected ancient lineages such as F*-M213, H*-M69 and C*-M216 that may be indicative of genetic signatures of the earliest settlers who reached India after their migration out of Africa.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Gene - Volume 526, Issue 2, 10 September 2013, Pages 96-106
Journal: Gene - Volume 526, Issue 2, 10 September 2013, Pages 96-106
نویسندگان
Shilpa Chennakrishnaiah, David Perez, Tenzin Gayden, Luis Rivera, Maria Regueiro, Rene J. Herrera,