Polymorphisms of transforming growth factor beta 1 (RS#1800468 and RS#1800471) and esophageal squamous cell carcinoma among Zhuangese population, China

► TGF-β1 RS#1800471 polymorphism upregulated the serum expression of this gene. ► TGF-β1 RS#1800471 polymorphism is related to ESCC risk and prognosis. ► TGF-β1 RS#1800471 polymorphism modified tumorigenesis of ESCC.