کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5911006 | 1570190 | 2013 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Whole genome sequence analysis of bovine G6P[11] rotavirus strain found in a child with gastroenteritis Whole genome sequence analysis of bovine G6P[11] rotavirus strain found in a child with gastroenteritis](/preview/png/5911006.png)
During the rotavirus strain surveillance in Slovenia, G6P[11] bovine rotavirus strain was detected in a 5Â months old boy with gastroenteritis. The strain was enrolled in a whole genome sequence analysis to determine its genome segment composition and genetic characteristics. Genotype composition for the whole genome was G6-P[11]-I2-R2-C2-M2-A13-N2-T6-E2-H3, reflecting similarities with bovine rotavirus strains. The bovine origin of the strain was confirmed in all genome segments, showing the highest nucleotide identity with bovine rotavirus strains and clustering of the RVA/Human-wt/SVN/SI-R56/07/2007/G6P[11] together with bovine rotavirus strains in phylogenetic analysis. This is the first bovine G6P[11] rotavirus strain with the whole genome analysis and the first report on rotavirus G6P[11] genotype detected in humans.
⺠Bovine-like G6P[11] rotavirus strain was found in a child with gastroenteritis. ⺠Whole genome analysis confirmed a bovine origin of human G6P[11] strain. ⺠Slovenian human and bovine G6P[11] strains represent different genome lineages. ⺠This is the first report on bovine-like G6P[11] rotavirus strain found in human.
Journal: Infection, Genetics and Evolution - Volume 13, January 2013, Pages 89-95