کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5911006 1570190 2013 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Whole genome sequence analysis of bovine G6P[11] rotavirus strain found in a child with gastroenteritis
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک بوم شناسی، تکامل، رفتار و سامانه شناسی
پیش نمایش صفحه اول مقاله
Whole genome sequence analysis of bovine G6P[11] rotavirus strain found in a child with gastroenteritis
چکیده انگلیسی

During the rotavirus strain surveillance in Slovenia, G6P[11] bovine rotavirus strain was detected in a 5 months old boy with gastroenteritis. The strain was enrolled in a whole genome sequence analysis to determine its genome segment composition and genetic characteristics. Genotype composition for the whole genome was G6-P[11]-I2-R2-C2-M2-A13-N2-T6-E2-H3, reflecting similarities with bovine rotavirus strains. The bovine origin of the strain was confirmed in all genome segments, showing the highest nucleotide identity with bovine rotavirus strains and clustering of the RVA/Human-wt/SVN/SI-R56/07/2007/G6P[11] together with bovine rotavirus strains in phylogenetic analysis. This is the first bovine G6P[11] rotavirus strain with the whole genome analysis and the first report on rotavirus G6P[11] genotype detected in humans.

► Bovine-like G6P[11] rotavirus strain was found in a child with gastroenteritis. ► Whole genome analysis confirmed a bovine origin of human G6P[11] strain. ► Slovenian human and bovine G6P[11] strains represent different genome lineages. ► This is the first report on bovine-like G6P[11] rotavirus strain found in human.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Infection, Genetics and Evolution - Volume 13, January 2013, Pages 89-95
نویسندگان
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