NINJURIN1 single nucleotide polymorphism and nerve damage in leprosy

► NINJURIN1 provides substrates for repair of Schwann cells after nerve injury. ► The NINJ1 gene plays an important role in nerve regeneration. ► The polymorphism in this gene is related to nerve damage in leprosy patients. ► Ninjurin asp110ala could be a valuable prognostic marker. ► The C allele (ala110) has increased susceptibility to nerve damage.