Coding and non-coding polymorphisms in VDR gene and susceptibility to pulmonary tuberculosis in tribes, castes and Muslims of Central India

► We studied VDR gene polymorphisms in TB patients showing different clinical outcomes ► Multiethnic samples were recruited to study ethnic variations in genetic predisposition ► We found significant association between VDR gene polymorphisms and clinical subtypes ► Study hints at ethnic differences in genetic susceptibility through VDR genotypes ► Data on genotype-phenotype correlation may help in diagnosis, screening and counselling