Low genetic polymorphism of merozoite surface proteins 7 and 10 in Colombian Plasmodium vivax isolates

▶ Pvmsp-7A, Pvmsp-7K and Pvmsp-10 genes display a low polymorphism among isolates. ▶ A single haplotype for Pvmsp-7A and Pvmsp-10 genes was found in Colombian parasites. ▶ The Pvmsp-7K gene displays 9 haplotypes in the Colombian parasite population. ▶ P. vivax msp-7 family members show different genetic variability patterns. ▶ Low variability of Pvmsp-7A and Pvmsp-7K might avoid inducing allele-specific immunity.