ApoptomiRs expression modulated by BCR-ABL is linked to CML progression and imatinib resistance

This study showed the modulation of apoptomiRs by BCR-ABL kinase activity and the deregulation of apoptomiRs and their predicted apoptotic target genes in different CML phases and after treatment with TK inhibitors. ApoptomiRs may be involved in the BCR-ABL+ cell apoptosis regulation.