کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5915240 1162799 2007 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Mechanism of osmoprotection by archaeal S-layers: A theoretical study
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شناسی مولکولی
پیش نمایش صفحه اول مقاله
Mechanism of osmoprotection by archaeal S-layers: A theoretical study
چکیده انگلیسی

Many Archaea possess protein surface layers (S-layers) as the sole cell wall component. S-layers must therefore integrate the basic functions of mechanical and osmotic cell stabilisation. While the necessity is intuitively clear, the mechanism of structural osmoprotection by S-layers has not been elucidated yet. The theoretical analysis of a model S-layer-membrane assembly, derived from the typical cell envelope of Crenarchaeota, explains how S-layers impart lipid membranes with increased resistance to internal osmotic pressure and offers a quantitative assessment of S-layer stability. These considerations reveal the functional significance of S-layer symmetry and unit cell size and shed light on the rationale of S-layer architectures.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Structural Biology - Volume 160, Issue 2, November 2007, Pages 190-199
نویسندگان
,