Transgenesis in the parasitic nematode Strongyloides ratti

- Strongyloides ratti can be transformed by gonadal microinjection of DNA constructs.
- Constructs with regulatory sequences from Strongyloides stercoralis are expressed in S. ratti.
- Transformation frequencies and expression patterns in the two are highly similar.
- S. ratti has major advantages over S. stercoralis in derivation of transgenic lines.