Differential gene expression in response to juvenile hormone analog treatment in the damp-wood termite Hodotermopsis sjostedti (Isoptera, Archotermopsidae)

► In termites, soldier-caste differentiation is induced by juvenile hormone (JH). ► Subtracted cDNA libraries were obtained from natural and JH analog-treated workers. ► Worker-specific digestive enzymes were downregulated by JH analog. ► Hexamerins and a putative nuclear protein were upregulated by JH analog. ► These upregulated genes are likely to be involved in JH-mediated caste regulation.