Developmental exposure to a serotonin agonist produces subsequent behavioral and neurochemical changes in the adult male prairie vole

► 5-HT acts as a developmental signal during early brain development. ► Early exposure to a 5-HT agonist, 5-MT, altered social and anxiety behaviors. ► Early exposure to 5-MT also decreased OT, AVP, and 5-HT staining in the brain. ► The prairie vole model may provide an excellent opportunity to study ASDs.